For the first time in his NFL career, New Orleans Saints quarterback Drew Brees may miss multiple games.

Ian Rapoport is reporting that Brees has a "ligament issue" on his throwing hand thumb.

Brees was injured in the first quarter of the Saints' 27-9 loss to the Los Angeles Rams when his throwing hand his hit by Rams defensive tackle Aaron Donald.

Brees, who has only missed one game in his 14-year NFL career, reportedly was set to meet with hand specialist Dr. Steve Shin, to determine the extent of the injury last night.